TEL: (212) 752-2020
FAX: (212) 821 0025
733 Third Ave. FL 20
New York, NY
10017 USA

SAFETY DATA SHEET

1. PRODUCT AND COMPANY IDENTIFICATION

1.1 Product identifiers

Product name

:

2-Butanone oxime

CAS-No.

:

96-29-7

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses

: Laboratory chemicals, Manufacture of substances

1.3 Details of the supplier of the safety data sheet

Distributor

: Continental Industries Group, Inc.

 

733

Third Avenue Fl. 20

 

Tel:

212-752-2020

 

New York, NY 10017

 

USA

1.4 Emergency telephone number

Chemtel Phone #

: 1-800-255-3924

International Phone #

: +01-813-248-0585

2. HAZARDS IDENTIFICATION

2.1 Classification of the substance or mixture

GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)

Flammable liquids (Category 4), H227 Acute toxicity, Dermal (Category 4), H312 Serious eye damage (Category 1), H318 Skin sensitisation (Category 1), H317 Carcinogenicity (Category 2), H351

For the full text of the H-Statements mentioned in this Section, see Section 16.

2.2 GHS Label elements, including precautionary statements

Pictogram

Signal word

Danger

Hazard statement(s)

 

H227

Combustible liquid.

H312

Harmful in contact with skin.

H317

May cause an allergic skin reaction.

H318

Causes serious eye damage.

H351

Suspected of causing cancer.

Precautionary statement(s)

 

P201

Obtain special instructions before use.

P202

Do not handle until all safety precautions have been read and

 

understood.

P210

 

Keep away from heat/sparks/open flames/hot surfaces. - No smoking.

P261

 

Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.

P272

 

Contaminated work clothing should not be allowed out of the workplace.

P280

 

Wear protective gloves/ protective clothing/ eye protection/ face

 

 

protection.

P302

+ P352

IF ON SKIN: Wash with plenty of soap and water.

P305

+ P351 + P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove

 

 

contact lenses, if present and easy to do. Continue rinsing.

P310

 

Immediately call a POISON CENTER or doctor/ physician.

P322

 

Specific measures (see supplemental first aid instructions on this label).

P333

+ P313

If skin irritation or rash occurs: Get medical advice/ attention.

P363

 

Wash contaminated clothing before reuse.

P370

+ P378

In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for

 

 

extinction.

P403

+ P235

Store in a well-ventilated place. Keep cool.

P405

 

Store locked up.

P501

 

Dispose of contents/ container to an approved waste disposal plant.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none

3. COMPOSITION/INFORMATION ON INGREDIENTS

3.1 Substances

 

 

 

 

 

Synonyms

:

Methyl ethyl ketoxime

 

 

Formula

: C4H9NO

 

 

Molecular weight

:

87.12 g/mol

 

 

CAS-No.

: 96-29-7

 

 

 

EC-No.

: 202-496-6

 

 

 

Index-No.

:

616-014-00-0

 

 

 

Hazardous components

 

 

 

 

 

Component

 

 

Classification

Concentration

 

2-Butanone oxime

 

 

 

 

 

 

 

 

Flam. Liq. 4; Acute Tox. 4; Eye

<= 100 %

 

 

 

 

Dam. 1; Skin Sens. 1; Carc. 2;

 

 

 

 

 

H227, H312, H317, H318,

 

 

 

 

 

H351

 

For the full text of the H-Statements mentioned in this Section, see Section 16.

4. FIRST AID MEASURES

4.1 Description of first aid measures

General advice

Move out of dangerous area.Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

5. FIREFIGHTING MEASURES

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx)

5.3 Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

5.4 Further information

Use water spray to cool unopened containers.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.

For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

6.3 Methods and materials for containment and cleaning up

Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations (see section 13). Keep in suitable, closed containers for disposal.

6.4 Reference to other sections

For disposal see section 13.

7. HANDLING AND STORAGE

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

7.3 Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control parameters

Components with workplace control parameters

Component

CAS-No.

Value

Control

 

Basis

 

 

 

parameters

 

 

2-Butanone oxime

96-29-7

TWA

10.000000 ppm

 

USA. Workplace Environmental

 

 

 

 

 

Exposure Levels (WEEL)

 

Remarks

Dermal Sensitization Notation

 

 

8.2 Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection

Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi- purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties

a)

Appearance

Form: clear, liquid

 

 

Colour: colourless

b)

Odour

No data available

c)

Odour Threshold

No data available

d)

pH

No data available

e)

Melting point/freezing

-29.5 °C (-21.1 °F) - OECD Test Guideline 102

 

point

 

f)

Initial boiling point and

59 - 60 °C (138 - 140 °F) at 20 hPa (15 mmHg) - lit.

 

boiling range

151 - 152 °C (304 - 306 °F) at 1,013 hPa (760 mmHg) - lit.

g)

Flash point

61.97 °C (143.55 °F) - closed cup

h)

Evaporation rate

No data available

i)

Flammability (solid, gas)

No data available

j)

Upper/lower

No data available

 

flammability or

 

 

explosive limits

 

k)

Vapour pressure

< 11 hPa (< 8 mmHg) at 20 °C (68 °F)

l)

Vapour density

3.01 - (Air = 1.0)

m)

Relative density

0.924 g/cm3 at 25 °C (77 °F)

n)

Water solubility

ca.100 g/l at 25 °C (77 °F) - OECD Test Guideline 105 - soluble

o)

Partition coefficient: n-

ca.log Pow: 0.63

 

octanol/water

 

p)

Auto-ignition

314 - 317 °C (597 - 603 °F)

 

temperature

 

q)

Decomposition

No data available

 

temperature

 

r)

Viscosity

No data available

s)

Explosive properties

No data available

 

t) Oxidizing properties

No data available

9.2

Other safety information

 

 

Dissociation constant

ca.12.45 at 25 °C (77 °F)

 

Relative vapour density

3.01 - (Air = 1.0)

10. STABILITY AND REACTIVITY

10.1 Reactivity

No data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

No data available

10.4 Conditions to avoid

Heat, flames and sparks.

10.5 Incompatible materials

Strong oxidizing agents, Strong acids

10.6 Hazardous decomposition products

Other decomposition products - No data available In the event of fire: see section 5

11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - male - 2,326 mg/kg (OECD Test Guideline 401)

LC50 Inhalation - Rat - male and female - 4 h - > 4.83 mg/l (OECD Test Guideline 403)

Dermal: No data available

LD50 Subcutaneous - Rat - 2,702 mg/kg

Skin corrosion/irritation

Skin - Rabbit

Result: No skin irritation (OECD Test Guideline 404)

Serious eye damage/eye irritation

Eyes - Rabbit

Result: Risk of serious damage to eyes. (OECD Test Guideline 405)

Respiratory or skin sensitisation

Buehler Test - Guinea pig

May cause sensitisation by skin contact. (OECD Test Guideline 406)

Germ cell mutagenicity in vitro assay

S. typhimurium

Result: negative

Drosophila melanogaster - male

Result: negative

Carcinogenicity

Limited evidence of carcinogenicity in animal studies

IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as

 

probable, possible or confirmed human carcinogen by IARC.

ACGIH:

No component of this product present at levels greater than or equal to 0.1% is identified as a

 

carcinogen or potential carcinogen by ACGIH.

NTP:

No component of this product present at levels greater than or equal to 0.1% is identified as a

 

known or anticipated carcinogen by NTP.

OSHA:

No component of this product present at levels greater than or equal to 0.1% is identified as a

 

carcinogen or potential carcinogen by OSHA.

Reproductive toxicity

No data available

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Additional Information

Repeated dose toxicity - Rat - male - Drinking - No observed adverse effect level - 25 mg/kg

Repeated dose toxicity - Rat - male and female - inhalation (vapour) - No observed adverse effect level - 0.009 mg/kg RTECS: EL9275000

To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

12. ECOLOGICAL INFORMATION

12.1 Toxicity

 

Toxicity to fish

semi-static test LC50 - Oryzias latipes - > 100 mg/l - 96 h

 

(OECD Test Guideline 203)

Toxicity to daphnia and

static test EC50 - Daphnia magna (Water flea) - ca. 201 mg/l - 48 h

other aquatic

(OECD Test Guideline 202)

invertebrates

 

Toxicity to algae

static test EC50 - Scenedesmus capricornutum (fresh water algae) - ca. 11.8

 

mg/l - 72 h

 

(OECD Test Guideline 201)

12.2 Persistence and degradability

12.3 Bioaccumulative potential

Bioaccumulation

Cyprinus carpio (Carp) - 42 d

 

- 2 mg/l

 

Bioconcentration factor (BCF): 0.5 - 0.6

 

(OECD Test Guideline 305C)

12.4 Mobility in soil

No data available

12.5 Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

12.6 Other adverse effects

No data available

13. DISPOSAL CONSIDERATIONS

13.1 Waste treatment methods

Product

Contact a licensed professional waste disposal service to dispose of this material. This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Offer surplus and non-recyclable solutions to a licensed disposal company.

Contaminated packaging

Dispose of as unused product.

14. TRANSPORT INFORMATION

 

DOT (US)

 

 

UN number: 1993

Class: 3

Packing group: III

Proper shipping name: Flammable liquids, n.o.s. (2-Butanone oxime)

Reportable Quantity (RQ):

Poison Inhalation Hazard: No

IMDG

UN number: 1993 Class: 3 Packing group: III EMS-No: F-E, S-E Proper shipping name: FLAMMABLE LIQUID, N.O.S. (2-Butanone oxime)

IATA

 

 

UN number: 1993

Class: 3

Packing group: III

Proper shipping name: Flammable liquid, n.o.s. (2-Butanone oxime)

15. REGULATORY INFORMATION

SARA 302 Components

No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.

SARA 313 Components

This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

SARA 311/312 Hazards

Fire Hazard, Acute Health Hazard

Massachusetts Right To Know Components

No components are subject to the Massachusetts Right to Know Act.

Pennsylvania Right To Know Components

 

 

 

CAS-No.

Revision Date

2-Butanone oxime

96-29-7

 

New Jersey Right To Know Components

 

 

 

CAS-No.

Revision Date

2-Butanone oxime

96-29-7

 

California Prop. 65 Components

This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

16. OTHER INFORMATION

Full text of H-Statements referred to under sections 2 and 3.

Acute Tox.

Acute toxicity

Carc.

Carcinogenicity

Eye Dam.

Serious eye damage

Flam. Liq.

Flammable liquids

H227

Combustible liquid.

H312

Harmful in contact with skin.

H317

May cause an allergic skin reaction.

H318

Causes serious eye damage.

H351

Suspected of causing cancer.

Skin Sens.

Skin sensitisation

HMIS Rating

 

Health hazard:

2

Chronic Health Hazard:

Flammability:

2

Physical Hazard

0

NFPA Rating

 

Health hazard:

2

Fire Hazard:

2

Reactivity Hazard:

0

Further information

The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Continental Industries Group, Inc. shall not be held liable for any damage resulting from handling or from contact with the above product.